The SYMPK antibody from MyBioSource.com is a Mouse Monoclonal antibody to PBK, SYM, and TOPK. This antibody recognizes Human, and Rat antigen. The SYMPK antibody has been validated for the following applications: Immunohistochemistry, and Western Blot.
Description
Mouse monoclonal SYMPK antibody
Symplekin is a protein that in humans is encoded by the SYMPK gene. This gene encodes a nuclear protein that functions in the regulation of polyadenylation and promotes gene expression. The protein forms a high-molecular weight complex with components of the polyadenylation machinery. It is thought to serve as a scaffold for recruiting regulatory factors to the polyadenylation complex. It also participates in 3'-end maturation of histone mRNAs, which do not undergo polyadenylation. The protein also localizes to the cytoplasmic plaques of tight junctions in some cell types